Expression of a GPR54-like but no agonistic effect of mammalian kisspeptins in trout
Kisspeptins and their G protein-coupled receptor, play a fundamental role in the control of reproductive function in mammals. Here we show that the anterior brain and testis of the trout express a GPR54-like transcript. Trout at 3 stages of maturation were submitted to in vivo treatment with large amounts or repeated injections of mouse or human C terminal decapeptides (KISS10). Mammalian KISS10 did not increase LH or testosterone hormone concentrations in the trout blood and were not able to stimulate ovulation or spermiation. Results even evoked a potential antagonistic effect of these peptides.