Results on systematics of the genus Centrophorus from the eastern Atlantic are yielded from an extensive study on body and skull morphometrics, dermal denticles, vertebral counting and fin rays. Our conclusions pointed out the validity of the following species inhabiting the area: C. squamosus, C. granulosus, C. lusitanicus and C. niaukang. The latter is recorded for the first time from the Atlantic, although it has appeared in several accounts either as C. granulosus or C. lusitanicus. We propose synonymising of Squalus uyato Raf., 1810 with an undetermined species of the genus Squalus, while Dalatias nocturnus Raf., 1810 should be regarded as junior synonym of C. granulosus.