Production of biologically active red seabream gonadotropins in a baculovirus system

Gen K., Soyano K., Okuzawa K., Kagawa H.

Date de parution: juillet 2008
Volume: 32
Number: 2 suppl.
Pagination: 218-219
Editeur: Société Française d'Ichtyologie

To obtain a large amount of biologically active fish gonadotropins (GtHs), recombinant red seabream GtHs were produced using a baculovirus expression system. Using a dual vector expression strategy, heterodimeric GtHs were successfully produced in silkworm larvae. These recombinant GtHs had the same bioactivity as purified GtHs, regarding the stimulation of in vitro steroid hormone production.

Mots-clés: Baculovirus expression system - FSH - LH - Recombinant protein - Red seabream
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