Modulation of the StAR protein and P450scc expressions in previtellogenic salmon oocytes by PCB congener 77

Sødahl J.A., Arukwe A.

Date de parution: juillet 2008
Volume: 32
Number: 2 suppl.
Pagination: 258-259
Editeur: Société Française d’Ichtyologie

Previtellogenic oocytes from Atlantic salmon were exposed to different concentrations of PCB77 using an in vitro agarose culture system for 3, 7 and 14 days. Overall, our results show time- and concentration-specific effects of PCB77 on key steroidogenic enzyme, P450scc and protein, StAr at the mrNA level, as well as protein level using immu-nohistochemical analysis.

Mots-clés: Atlantic salmon - Histology - PCB77 - Previtellogenic oocytes - Q-PCR
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