Bathygobius karachiensis is described from the Karachi coast of Pakistan. The fish was found at depths ranging from 1 ou 2 m. It is characterized by anterior and posterior oculoscapular canals interconnected (4 supra opercular pores); 35-36 scales along body; 14-15 transverse series of scales; cheek and opercle scaleless; predorsal scales 13-21 reaching slightly anterior to hind preopercular margin; a skinny flap on anterior nostril; pectoral fin with 5 upper rays free, each with 4-5 branches. Body and head brown; first dorsal fin with 4 rows of dark spots; 5 saddle-like blotches on back and upper part of flank; mid-lateral line with 7 elongate spots; a dark spot behind eye, another on base of free pectoral fin rays.